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Title	Alternatives to blood transfusion in transfusion medicine / edited by Alice Maniatis, Philippe Van der Linden, Jean-François Hardy
Publish Info	Chichester, West Sussex, UK ; Hoboken, NJ : Wiley-Blackwell, 2011
Edition	2nd ed

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Wright State Dunbar 3rd Floor RM171 .A623 2011 AVAILABLE

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Contents

Contributors List

Part 1 History and Development of Transfusion Medicine 1

1 From Blood Transfusion to Transfusion Medicine / Alice Maniatis 3

Part 2 Allogeneic Blood Usage---Risks and Benefits 9

2 Allogeneic Blood Components / Sheila MacLennan 11

3 Current Information on the Infectious Risks of Allogeneic Blood Transfusion / John A. J. Barbara 21

4 Immunological Complications of Blood Transfusion / Marcela Contreras 31

5 Immunomodulation and Allogeneic Blood Transfusion / Anneke Brand 47

6 Pathogen Inactivation of Blood Components / Chris Prowse 60

7 The Benefits of Allogeneic Erythrocyte Transfusion: What Evidence Do We Have? / Benjamin Thomas 68

Part 3 Volume Replacement 83

Section 1 Plasma and Albumin 85

8 Plasma and Albumin / Philippe L. Baele 87

Section 2 Crystalloids and Synthetic Colloids 109

9 Pharmacology of Intravenous Fluids / Michael F.M. James 111

10 Crystalloids versus Colloids: The Controversy / Hengo Haljamae 119

11 Effects of Synthetic Colloids on Hemostasis / Gisela Scharbert 137

12 Hydroxyethyl Starch and Renal Dysfunction / Bertrand Guidet 150

13 Choice of a Synthetic Colloid for Surgery / Joachim Boldt 158

14 Choice of Colloid for Intensive Care Patients / Yalcin Inel 168

15 Hypertonic Saline Solutions for the Initial Treatment of Patients with Traumatic Injuries / Michael A. Dubick 179

16 Hyperchloremic Acidosis / Andre Vercueil 194

Part 4 Tolerance of Anemia 203

17 Basic Principles of Oxygen Transport and Calculations / Davide Simion 205

18 Assessment of Tissue Oxygenation / Philippe Van der Linden 210

19 Tissue Oxygenation and Blood Transfusion / Joachim Boldt 218

20 Anemia and Cardiovascular Disease / Helen Melita 229

Part 5 Perioperative Hemostasis 253

21 Monitoring of Hemostasis in the Perioperative Setting / Eva Schaden 255

22 Antifibrinolyties in Open-Heart Surgery / Wulf Dietrich 267

23 Efficacy and Safety of Recombinant Activated Factor VII to Control Bleeding in Nonhemophiliac Patients / Philippe Van der Linden 278

Part 6 Transfusion Triggers 293

24 Role of Hemoglobin/Hematocrit / A. Gerson Greenburg 295

25 Calculation of Blood Loss / Mark E. Brecher 303

26 Management of Massive Transfusion / Marc Samama 313

Part 7 Alternatives to Allogeneic Blood Transfusion 329

Section 1 Pharmaceutical Approaches 331

27 Iron Deficiency: Causes, Diagnosis, and Management / Elvira Bisbe 335

28 Current Status of Perisurgical Erythropoietin Therapy / Lawrence T. Goodnough 350

29 Erythropoietin and Iron Therapy in Patients with Renal Failure / Francesco Locatelli 357

30 Hemoglobin-based Blood Substitutes / Maurice Lamy 368

31 Perfluorocarbon Emulsions / Pedro Cabrales 380

Section 2 Surgical Techniques 389

32 Minimally Invasive Cardiac Surgery: Impact on Blood Loss and Transfusion / Fraser Rubens 391

33 Adjunctive Strategies to Impact Blood Transfusion in Cardiac Surgery / Fraser Rubens 408

Section 3 Anesthetic Techniques 419

34 Anesthetic Techniques to Reduce Blood Loss / Dafydd Thomas 421

35 Controlled Hypotension Decreases Blood Transfusion Requirement: Fact or Fallacy? / Richard P. Dutton 430

36 Acute Normovolemic Hemodilution / Philippe Van der Linden 439

37 Hyperoxic Hemodilution / Oliver Habler 450

38 Intraoperative and Postoperative Cell Salvage / Hans Gombotz 458

Section 4 Special Settings 475

39 Anemia and Red Blood Transfusion in Critical Care / Tim Walsh 477

40 Red Blood Cell Transfusions and Alternatives to Treat the Anemia of Prematurity / Ronald G. Strauss 490

41 Transfusion Alternatives in Orthopedic Surgery / Jorge Cuenca 498

42 Transfusion Alternatives in Obstetrics / Christian Breymann 509

Part 8 Legal and Ethical Issues in Transfusion Medicine 521

43 Ethical Aspects of Informed Consent: American Models / Ronald E. Domen 523

44 Blood Transfusions, Jehovah's Witnesses, and the American Patients' Rights Movement / Charles H. Baron 531

Part 9 Cost Issues 557

45 The Cost and Cost-Effectiveness of Allogeneic and Autologous Blood / Brian Custer 559

46 Autologous Blood Predonation in Cardiac Surgery / Wulf Dietrich 569

47 Cost-Effectiveness of Pharmacological Alternatives / Brian Hutton 575

Index 581

Description xii, 594 pages : illustrations ; 26 cm

Note Revised edition of: Transfusion medicine and alternatives to blood transfusion / NATA (Network for Advancement of Transfusion Alternatives). c2000

Includes bibliographical references and index

Summary Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion. Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products. The new edition is a key reference source for all those involved in the practice of blood management and conservation

Contents History and development of transfusion medicine -- Allogeneic blood usage: risks and benefits -- Volume replacement -- Tolerance of anemia -- Perioperative hemostasis -- Transfusion triggers -- Alternatives to allogeneic blood transfusion -- Legal and ethical issues in transfusion medicine -- Cost issues

Subjects Blood -- Transfusion

Blood -- Transfusion -- Complications

Blood substitutes -- Therapeutic use

Blood Transfusion, Autologous -- trends

Blood Substitutes -- therapeutic use

Hemostasis, Surgical -- trends

Blood Transfusion

Alt Name Maniatis, Alice

Linden, Philippe van der

Hardy, Jean-François

Other Titles Transfusion medicine and alternatives to blood transfusion

LC NO RM171 .A623 2011

Nlm No 2010 M-889

WB 356 A466 2011

Dewey No 615/.39 22

OCLC # 439472175

ISBN 9781405163217

1405163216

9781444319583

1444319582

Isn/Std # (OCoLC)439472175 (OCoLC)755220592 (OCoLC)987703001

LCCN 2009038757

	Contributors List
Part 1	History and Development of Transfusion Medicine	1
1	From Blood Transfusion to Transfusion Medicine / Alice Maniatis	3
Part 2	Allogeneic Blood Usage---Risks and Benefits	9
2	Allogeneic Blood Components / Sheila MacLennan	11
3	Current Information on the Infectious Risks of Allogeneic Blood Transfusion / John A. J. Barbara	21
4	Immunological Complications of Blood Transfusion / Marcela Contreras	31
5	Immunomodulation and Allogeneic Blood Transfusion / Anneke Brand	47
6	Pathogen Inactivation of Blood Components / Chris Prowse	60
7	The Benefits of Allogeneic Erythrocyte Transfusion: What Evidence Do We Have? / Benjamin Thomas	68
Part 3	Volume Replacement	83
Section 1	Plasma and Albumin	85
8	Plasma and Albumin / Philippe L. Baele	87
Section 2	Crystalloids and Synthetic Colloids	109
9	Pharmacology of Intravenous Fluids / Michael F.M. James	111
10	Crystalloids versus Colloids: The Controversy / Hengo Haljamae	119
11	Effects of Synthetic Colloids on Hemostasis / Gisela Scharbert	137
12	Hydroxyethyl Starch and Renal Dysfunction / Bertrand Guidet	150
13	Choice of a Synthetic Colloid for Surgery / Joachim Boldt	158
14	Choice of Colloid for Intensive Care Patients / Yalcin Inel	168
15	Hypertonic Saline Solutions for the Initial Treatment of Patients with Traumatic Injuries / Michael A. Dubick	179
16	Hyperchloremic Acidosis / Andre Vercueil	194
Part 4	Tolerance of Anemia	203
17	Basic Principles of Oxygen Transport and Calculations / Davide Simion	205
18	Assessment of Tissue Oxygenation / Philippe Van der Linden	210
19	Tissue Oxygenation and Blood Transfusion / Joachim Boldt	218
20	Anemia and Cardiovascular Disease / Helen Melita	229
Part 5	Perioperative Hemostasis	253
21	Monitoring of Hemostasis in the Perioperative Setting / Eva Schaden	255
22	Antifibrinolyties in Open-Heart Surgery / Wulf Dietrich	267
23	Efficacy and Safety of Recombinant Activated Factor VII to Control Bleeding in Nonhemophiliac Patients / Philippe Van der Linden	278
Part 6	Transfusion Triggers	293
24	Role of Hemoglobin/Hematocrit / A. Gerson Greenburg	295
25	Calculation of Blood Loss / Mark E. Brecher	303
26	Management of Massive Transfusion / Marc Samama	313
Part 7	Alternatives to Allogeneic Blood Transfusion	329
Section 1	Pharmaceutical Approaches	331
27	Iron Deficiency: Causes, Diagnosis, and Management / Elvira Bisbe	335
28	Current Status of Perisurgical Erythropoietin Therapy / Lawrence T. Goodnough	350
29	Erythropoietin and Iron Therapy in Patients with Renal Failure / Francesco Locatelli	357
30	Hemoglobin-based Blood Substitutes / Maurice Lamy	368
31	Perfluorocarbon Emulsions / Pedro Cabrales	380
Section 2	Surgical Techniques	389
32	Minimally Invasive Cardiac Surgery: Impact on Blood Loss and Transfusion / Fraser Rubens	391
33	Adjunctive Strategies to Impact Blood Transfusion in Cardiac Surgery / Fraser Rubens	408
Section 3	Anesthetic Techniques	419
34	Anesthetic Techniques to Reduce Blood Loss / Dafydd Thomas	421
35	Controlled Hypotension Decreases Blood Transfusion Requirement: Fact or Fallacy? / Richard P. Dutton	430
36	Acute Normovolemic Hemodilution / Philippe Van der Linden	439
37	Hyperoxic Hemodilution / Oliver Habler	450
38	Intraoperative and Postoperative Cell Salvage / Hans Gombotz	458
Section 4	Special Settings	475
39	Anemia and Red Blood Transfusion in Critical Care / Tim Walsh	477
40	Red Blood Cell Transfusions and Alternatives to Treat the Anemia of Prematurity / Ronald G. Strauss	490
41	Transfusion Alternatives in Orthopedic Surgery / Jorge Cuenca	498
42	Transfusion Alternatives in Obstetrics / Christian Breymann	509
Part 8	Legal and Ethical Issues in Transfusion Medicine	521
43	Ethical Aspects of Informed Consent: American Models / Ronald E. Domen	523
44	Blood Transfusions, Jehovah's Witnesses, and the American Patients' Rights Movement / Charles H. Baron	531
Part 9	Cost Issues	557
45	The Cost and Cost-Effectiveness of Allogeneic and Autologous Blood / Brian Custer	559
46	Autologous Blood Predonation in Cardiac Surgery / Wulf Dietrich	569
47	Cost-Effectiveness of Pharmacological Alternatives / Brian Hutton	575
	Index	581