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Latest Original Research

Carfilzomib-associated thrombotic microangiopathy: clinical features and outcomes
Adrien Joseph and others
Background and hypothesis Carfilzomib, a new proteasome inhibitor indicated for patients with relapsed/refractory myeloma, has been associated with cases of thrombotic microangiopathy (CFZ-TMA). The role of variants in the complement alternative ...
Sex differences in chronic kidney disease-related complications and mortality across levels of glomerular filtration rate
Gianmarco Lombardi and others
Background and hypothesis Chronic kidney disease (CKD) is a growing global health concern. Recent research has indicated sex disparities in CKD-related complications, yet the impact of sex differences on critical kidney function levels that trigger ...
2-Step-Scores with optional nephropathology for the prediction of adverse outcomes for brain-dead donor kidneys in Eurotransplant
Angela Ernst and others
Background and hypothesis The decision for acceptance or discard of the increasingly rare and marginal brain-dead donor kidneys in Eurotransplant (ET) countries has to be made without solid evidence. Thus, we developed and validated flexible ...
Hemoadsorption: Consensus report of the 30th Acute Disease Quality Initiative workgroup
Ghada Ankawi and others
Adsorption-based extracorporeal therapies have been subject to technical developments and clinical application for close to five decades. More recently, new technological developments in membrane and sorbent manipulation have made it possible to ...
Rituximab or cyclosporine a for the treatment of membranous nephropathy: Economic evaluation of the MENTOR trial
Matthew Kadatz and others
Background and hypothesis The MENTOR trial (MEmbranous Nephropathy Trial Of Rituximab) showed that rituximab was noninferior to cyclosporine in inducing complete or partial remission of proteinuria and was superior in maintaining proteinuria ...

Latest Reviews

Iron biology
Lucia Del Vecchio and others
Iron is a fundamental element for biological life, starting from bacteria till humans. Iron is essential for cell function and survival, energy production and metabolism, whereas increased levels cause oxidative stress. It is also a constituent of ...
Hypoxia-inducible factor prolyl hydroxylase inhibitors for anaemia in chronic kidney disease: a document by the European Renal Best Practice board of the European Renal Association
Sokratis Stoumpos and others
Anaemia is a common complication of chronic kidney disease (CKD) and is associated with poor long-term outcomes and quality of life. The use of supplemental iron, erythropoiesis stimulating agents (ESAs) and blood transfusions has been the mainstay ...
Klotho in pregnancy and intrauterine development – Potential clinical implications: a review from the European Renal Association CKD-MBD Working Group
Mehmet Kanbay and others
Intrauterine development is crucial for life-long health; therefore, elucidation of its key regulators is of interest for their potential prognostic and therapeutic implications. Originally described as a membrane-bound anti-aging protein, Klotho ...
Physical exercise: a polypill against chronic kidney disease
Pedro L Valenzuela and others
We are currently facing a pandemic of physical inactivity that might contribute to the growing prevalence of chronic kidney disease (CKD). Here, we summarize currently available evidence on the association between physical activity and CKD, and also ...
How can inhibition of glucose and sodium transport in the early proximal tubule protect the cardiorenal system?
Volker Vallon
What mechanisms can link the inhibition of sodium-glucose cotransporter 2 (SGLT2) in the early proximal tubule to kidney and heart protection in patients with and without type 2 diabetes? Due to physical and functional coupling of SGLT2 to other ...
Impact Factor
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ERA Journal Club e-seminars

The ERA Journal Club e-seminars aim to initiate an open discussion among the nephrology community on how the results obtained in the recent trials can be applied to the needs of patients. 

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Article: Transient acute kidney injury after chimeric antigen receptor T-cell therapy in patients with hematological malignancies

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Treatment of Secondary Hyperparathyroidism in Non-Dialysis CKD: An appraisal 2022

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Management of antineutrophil cytoplasmic antibody–associated vasculitis with glomerulonephritis as proposed by the ACR 2021, EULAR 2022 and KDIGO 2021 guidelines/recommendations 

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Sodium-glucose cotransporter 2 inhibition in primary and secondary glomerulonephritis

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