Clathrin-independent carrier
Clathrin-independent carriers (CLICs) are prevalent tubulovesicular membranes responsible for non-clathrin mediated endocytic events. They appear to endocytose material into GPI-anchored protein-enriched early endosomal compartment (GEECs). Collectively, CLICs and GEECs comprise the Cdc42-mediated CLIC/GEEC endocytic pathway, which is regulated by GRAF1.[1][2][3]
  1. ^ Lundmark, R.; Doherty, G.J.; Howes, M.T.; et al. (November 2008). "The GTPase-Activating Protein GRAF1 Regulates the CLIC/GEEC Endocytic Pathway". Current Biology. 18 (22): 1802–8. doi​:​10.1016/j.cub.2008.10.044​. PMC 2726289. PMID 19036340.
  2. ^ Rossatti, P.; Ziegler, L.; Schregle, R; et al. (November 2019). "Cdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular Invaginations of the Plasma Membrane". Cells. 8 (11): 1388. doi​:​10.3390/cells8111388​. PMC 6912536. PMID 31690048.
  3. ^ Elkin, S.R.; Lakoduk, A.M.; Schmid, S.L. (May 2016). "Endocytic pathways and endosomal trafficking: a primer". Wiener Medizinische Wochenschrift. 166 (7–8): 196–204. doi​:​10.1007/s10354-016-0432-7​. PMC 4873410. PMID 26861668.

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Last edited on 3 January 2021, at 02:34
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