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File:HIV Membrane fusion panel.svg

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English: Mechanism of Viral Entry/Membrane Fusion

1. Initial interaction between gp120 and CD4. 2. Conformational change in gp120 allows for secondary interaction with CXCR4. 3. The distal tips of gp41 are inserted in to the cellular membrane.

4. gp41 undergoes significant conformational change; folding in half and forming coiled-coils. This process pulls the viral and cellular membranes together, fusing them.
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Author Mike Jones
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inception

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Date/TimeThumbnailDimensionsUserComment
current06:03, 3 November 2023Thumbnail for version as of 06:03, 3 November 20231,644 × 324 (2.09 MB)RasbakCCR5 replaced by CXCR4
22:13, 2 November 2023Thumbnail for version as of 22:13, 2 November 20231,644 × 324 (2.09 MB)RasbakCCR5 replaced by CXCR4
22:02, 2 November 2023Thumbnail for version as of 22:02, 2 November 20231,644 × 324 (2.09 MB)RasbakCCR5 replaced by CXCR4
19:19, 18 April 2013Thumbnail for version as of 19:19, 18 April 20131,644 × 324 (1.63 MB)Adenosinedecorated the interior of the virion and capitalised CCR5 and made gp41 coil as a bundle as opposed to scissoring
01:10, 12 March 2013Thumbnail for version as of 01:10, 12 March 20131,644 × 324 (1.17 MB)AdenosineUser created page with UploadWizard
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