Jamule's mother is from Andalusia and his father from Lebanon. Immediately after birth, his parents moved to Mülheim and one year later to Essen, where he grew up in the borough Kray. However, he went to school in Mülheim so he constantly commuted. His mother Maria Serrano Serrano was a dancer and member of the pop group Passion Fruit and died through an airplane crash in 2001 (Crossair Flight 3597) when Jamule was five years old.
In October 2018 he signed a contract with Life is Pain, a label from the German rapper PA Sports. According to PA Sports statement, Jamule got the biggest advance payment for a German newcomer ever. "Ich hol dich ab" was his first top-10 single. With the song "Unterwegs" he worked together with the rap producer team KitschKrieg and reached the top of the Official German singles chart in September 2020.