Mid-Cambridge, also known as "Area 6", is a neighborhood of Cambridge, Massachusetts. It is bounded by Massachusetts Avenue on the south and west, Prospect Street on the east, and Hampshire Street, the Somerville border, Kirkland Street, Quincy Street, and Cambridge Street on the north.

Historic Christ the King Presbyterian Church on Prospect Street in Mid-Cambridge was constructed in 1851 by Alexander Esty

In 2005, the neighborhood had a population of 13,285 residents in 5,989 households. The average household income was $50,410.

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42°22′21.50″N 71°06′34.75″W / 42.3726389°N 71.1096528°W / 42.3726389; -71.1096528