Quinazoline alkaloids are natural products from the group of alkaloids, which are chemically derived from quinazoline. Some quinazoline alkaloids show bronchodilatory effects and stimulate respiration.[1] An abortive effect was also found for vasicine in studies on rats and rabbits.[2]

Quinazoline, the parent compound of the quinazoline alkaloids.

Examples edit

About 70 alkaloids with a quinazoline structure are known, which are mostly further classified as simple quinazolinones, pyrroloquinazolines, pyrido[2,1-b]quinazolines and indoloquinazolines.[1]

Occurrence edit

Quinazoline alkaloids can be found mainly in plants, such as acanthaceae (Adhatoda vasica), rutaceae, saxifragaceae (Dichroa febrifuga) and in linaria species (Scrophulariaceae) and peganum harmala (Fam. Zygophyllaceae); also in animals (e. g. tetrodotoxin) and bacteria.

Links edit

References edit

  1. ^ a b Entry on Peganin. at: Römpp Online. Georg Thieme Verlag, retrieved 24. März 2016.
  2. ^ Abortive Wirkung von Lungenkraut: Adhatoda Vasika: Vasaka at the Wayback Machine (archived 2014-06-11) (PDF; 62 kB).