Title Active pharmaceutical ingredients in synthesis : catalytic processes in research and development / Anthony J. Burke, Carolina S. Marques, Nicholas J. Turner, Gesine J. Hermann.

Descript 1 online resource Contents Catalysis and Prerequisites for the Modern Pharmaceutical Industry Landscape -- Catalytic Process Design: The Industrial Perspective -- Hydrogenation, Hydroformylation, and Other Reductions -- Oxidation: Nobel Prize Chemistry Catalysis -- Catalytic Addition Reactions -- Catalytic Cross-Coupling Reactions -- Nobel Prize Catalysis -- Catalytic Metathesis Reactions: Nobel Prize Catalysis -- Catalytic Cycloaddition Reactions: Coming Full Circle -- Catalytic Cyclopropanation Reactions -- Catalytic C-H Insertion Reactions -- Phase-Transfer Catalysis -- Biocatalysis -- Index. Bibliog. Includes bibliographical references and index. Summary Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis. Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutial Industry Landscape; Catalytic Process Design - The Industrial Perspective; Hydrogenation, Hydroformylation and Other Reductions; Oxidation; ; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis.-Provides the reader with an updated clear view of the current state of the challenging field of catalysis for API production -Focuses on the application of catalytic methods for the synthesis of known APIs -Presents every key reaction, including Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, and many more -Includes recent patent literature for completeness Covering a topic of great interest for synthetic chemists and R & D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs. Local Note John Wiley and Sons Wiley Online Library UBCM All Obooks Marc m o d Subject Pharmaceutical biotechnology. Bioactive compounds -- Synthesis. Catalysis. Catalysis MEDICAL -- Pharmacology. Catalysis Pharmaceutical biotechnology Alt Author Marques, Carolina Silva, 1981- author. Turner, N. J. (Nicholas J.), author. Hermann, Gesine J., author. ISBN 9783527807246 (electronic bk.) 3527807241 (electronic bk.) 9783527807253 (electronic bk. ; oBook) 352780725X (electronic bk. ; oBook) 3527342419 9783527342419 9783527342419