Title Affinity and efficacy : the components of drug-receptor interactions / Frederick J. Ehlert.

Descript 1 online resource Bibliog. Includes bibliographical references. Contents Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors. Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - Worldwide Subject Drug receptors. Drugs -- Effectiveness. Drug-nutrient interactions. Pharmaceutical chemistry. Carrier proteins. Radioligand assay. Receptors, Drug Food-Drug Interactions Chemistry, Pharmaceutical Ligand-Gated Ion Channels Carrier Proteins Radioligand Assay Receptors, G-Protein-Coupled MEDICAL -- Pharmacology. Radioligand assay. (OCoLC)fst01088255 Carrier proteins. (OCoLC)fst00847934 Drug-nutrient interactions. (OCoLC)fst00898756 Drug receptors. (OCoLC)fst00898699 Drugs -- Effectiveness. (OCoLC)fst00898808 Pharmaceutical chemistry. (OCoLC)fst01060115 Alt Title Components of drug-receptor interactions ISBN 9789814324229 (electronic bk.) 9814324221 (electronic bk.) 9789814322560 9814322563