Abstract
Genetic heterogeneity within Sicily was investigated on the basis of ACP1, ADA, ESD, GLO1, PGD, PGM1, PGM2, SODA, ABO, and MN gene frequencies, and compared to those of other regions of Italy for which these same loci have been examined. Correspondence analysis revealed no differences within the island, at least at the provincial level, but showed genetic differentiation among Italian regions, distinctly clustering northern, central, and southern populations, respectively. These data indicate a close relationship between Sicily and southern Italy. In addition, the contribution of Middle Eastern populations to the gene pool of Sicily was evident.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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ABO Blood-Group System / genetics
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Acid Phosphatase / blood
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Acid Phosphatase / genetics
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Adenosine Deaminase / blood
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Adenosine Deaminase / genetics
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Blood Group Antigens / genetics*
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Carboxylesterase*
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Carboxylic Ester Hydrolases / blood
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Carboxylic Ester Hydrolases / genetics
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Erythrocytes / enzymology*
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Female
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Gene Frequency*
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Humans
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Lactoylglutathione Lyase / blood
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Lactoylglutathione Lyase / genetics
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MNSs Blood-Group System / genetics
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Male
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Middle East / ethnology
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Phosphoglucomutase / blood
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Phosphoglucomutase / genetics
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Phosphogluconate Dehydrogenase / blood
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Phosphogluconate Dehydrogenase / genetics
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Sicily
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Superoxide Dismutase / blood
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Superoxide Dismutase / genetics
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White People / genetics*
Substances
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ABO Blood-Group System
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Blood Group Antigens
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MNSs Blood-Group System
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Phosphogluconate Dehydrogenase
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Superoxide Dismutase
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Carboxylic Ester Hydrolases
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Carboxylesterase
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ESD protein, human
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Acid Phosphatase
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Adenosine Deaminase
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Lactoylglutathione Lyase
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Phosphoglucomutase