pubmed.ncbi.nlm.nih.gov
COVID-19 Information
Public health information (CDC)
Research information (NIH)
SARS-CoV-2 data (NCBI)
Prevention and treatment information (HHS)
Español
Log in

Advanced
Polymorphisms of mtDNA control region in Tunisian and Moroccan populations: an enrichment of forensic mtDNA databases with Northern Africa data
Chiara Turchi et al. Forensic Sci Int Genet. 2009 Jun.
Abstract
Current forensic mitochondrial (mt)DNA databases are limited in representative population data of African origin. We investigated HVS-I/HVS-II sequences of 120 Tunisian and Moroccan healthy male donors applying stringent quality criteria to assure high quality of the data and phylogenetic alignment and notation of the sequences. Among 64 Tunisians, 56 different haplotypes were observed and the most common haplotype (16187T 16189C 16223T 16264T 16270T 16278T 16293G 16311C 73G 152C 182T 185T 195C 247A 263G 309.1C 315.1C; haplogroup (hg) L1b) was shared by four individuals. 56 Moroccans could be assigned to 52 different haplotypes where the most common haplotype was of West Eurasian origin with the hg H sequence motif 263G 315.1C and variations in the HVS-II polyC-stretch (309.1C 309.2C) shared by six samples. The majority of the observed haplotypes belong to the west Eurasian phylogeny (50% in Tunisians and 62.5% in Moroccans). Our data are consistent with the current phylogeographic knowledge displaying the occurrence of sub-Saharan haplogroup L sequences, found in 48.4% of Tunisians and 25% of Moroccans as well as the presence of the two re-migrated haplogroups U6 (7.8% and 1.8% in Tunisians and Moroccans, respectively) and M1 (1.6% in Tunisians and 8.9% in Moroccans).
Similar articles
Mitochondrial DNA population data of HVS-I and HVS-II sequences from a northeast German sample.
Tetzlaff S, et al. Forensic Sci Int. 2007.PMID: 17331686
African-American mitochondrial DNAs often match mtDNAs found in multiple African ethnic groups.
Ely B, et al. BMC Biol. 2006. PMID: 17038170Free PMC article.
Forensic genetic analysis of mitochondrial DNA hypervariable region I/II sequences: an expanded Korean population database.
Jin HJ, et al. Forensic Sci Int. 2006.PMID: 15990264
Recent progress in mitochondrial DNA analysis.
Umetsu K, et al. Leg Med (Tokyo). 2005.PMID: 15939655 Review.
Phylogeographic investigations: the role of trees in forensic genetics.
Salas A, et al. Forensic Sci Int. 2007.PMID: 16814504 Review.
See all similar articles
Cited by 10 articles
Genetics and genomic medicine in Tunisia.
Elloumi-Zghal H, et al. Mol Genet Genomic Med. 2018.PMID: 29663716 Free PMC article.
Evidence for prehistoric origins of the G2019S mutation in the North African Berber population.
Ben El Haj R, et al. PLoS One. 2017. PMID: 28723952Free PMC article.
Early Holocenic and Historic mtDNA African Signatures in the Iberian Peninsula: The Andalusian Region as a Paradigm.
Hernández CL, et al. PLoS One. 2015.PMID: 26509580 Free PMC article.
Y-chromosome and mtDNA genetics reveal significant contrasts in affinities of modern Middle Eastern populations with European and African populations.
Badro DA, et al. PLoS One. 2013. PMID: 23382925Free PMC article.
Mitochondrial DNA control region variation from samples of the Moroccan population.
Aboukhalid R, et al. Int J Legal Med. 2013.PMID: 23283404
See all "Cited by" articles
MeSH terms
Substances
Related information
MedGen
PubChem Compound (MeSH Keyword)
LinkOut - more resources
Full Text Sources
ClinicalKey
Elsevier Science
NCBI Literature Resources
MeSH PMC BookShelf
FOLLOW NCBI
Follow NLM
National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
Copyright
FOIA
Privacy
Help
Accessibility
Careers
NLMNIHHHSUSA.gov
Title & authorsAbstractSimilar articlesCited byMeSH termsSubstancesRelated informationLinkOut - more resources