| Note |
Includes bibliographical references and index. |
| Contents |
NMR spectroscopy in the European regulatory dossier / S. Branch -- Analysis of drugs / B.W.K. Diehl and U. Holzgrabe -- pH-dependent NMR measurements / G. Hägele and U. Holzgrabe -- Complexation behaviour of drugs studied by NMR / B.W.K. Diehl and U. Holzgrabe -- Determination of the isometric composition of drugs / B.W.K. Diehl and U. Holzgrabe -- On-line coupling of HPLC or SFC / K. Albert -- NMR of body fluids / U. Holzgrabe -- NMR as a tool in drug research / G. Gemmecker -- Ligand-cyclodextrin complexes / B. Chankvetadze, G. Blaschke and G. Pintore -- Ligand-membrane interaction / J.K. Seydel -- Solid-state NMR in drug analysis / I. Wawer -- MR imaging and MR spectroscopy / I. Wawer. |
| Summary |
Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (& 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis. This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition o. |
| Note |
Use copy Restrictions unspecified star MiAaHDL |
| Reproduction |
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. MiAaHDL |
| Note |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
| Retention |
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Note |
Print version record. |
| Subject |
Drug development.
|
|
Drugs -- Analysis.
|
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Nuclear magnetic resonance spectroscopy.
|
|
Electronic books. |
| Local Subj. |
Wiley ebook collection.
|
| Alt Author |
Wawer, I. (Iwona)
|
|
Diehl, B. (Bernd)
|
| Standard # |
9783527613656 (electronic bk.) |
|
352761365X (electronic bk.) |
|
9783527613649 |
|
3527613641 |
|
3527300929 |
|
9783527300921 |
|
10.1002/9783527613649 doi |
|
