Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Glucosamine and 4-Phenylbutyric Acid

Research Papers that Mention the Interaction

In addition, GlcN stimulated proinflammatory cytokine release and PBA prevented these effects.
Very low concentrations of 4-phenyl butyric acid PBA , a chemical chaperone) inhibited only the overactivation of ER stress and UPR elicited by GlcN , leaving unaltered the part physiologically activated during differentiation, and reversed the inhibitory effect of GlcN on differentiation.
Biochimica et biophysica acta  •  2016  |  View Paper