21 captures
06 Feb 2006 - 09 Jun 2010
About this capture
Jennifer A. Swift
Associate Professor
Director of Undergraduate studies
Department of Chemistry 
Georgetown University
37th and O Streets NW
Washington, DC 20057-1227
Office: 647 Reiss Science
Phone: 202-687-5567
Fax: 202-687-6209
Lab web sitehttp://georgetown.edu/faculty/jas2
Education /
B.A. magna cum laude, 1991 Bowdoin College
Ph. D. 1997 Yale University
Postdoctoral associate, 1997-1999 Dept of Chemical Engineering & Materials Science, University of Minnesota,
NSF CAREER Award (2001); CNDLS Teaching, Learning & Technology Fellow (2003-2004); Camille Dreyfus Teacher-Scholar Award (2004); American Crystallography Association Margaret C. Etter Award (2005); College Dean’s Award for Excellence in Teaching (2005)
TeachingOrganic Chemistry Lecture I, Organic Chemistry Lab I & II, Solid State Organic Chemistry
Research InterestsResearch in the Swift lab is directed toward gaining a more detailed understanding of the mechanisms by which molecular crystals nucleate and grow. Most of the projects in this research area are quite interdisciplinary - meaning students will be expected to gain experience in at least a few different areas of chemistry including x-ray crystallography, atomic force microscopy (AFM), organic synthesis, and computational modeling. 
1.  Crystal Growth in Human Disease/Biomineralization
Cholesterol is a major constituent of human gallstones and arterial plaques.  Using in situ AFM, the real-time crystal growth of this important material can be elucidated.  Unprecedented details on the crystal's surface structure, growth rates and growth mechanisms are obtained in model bile solutions and in a variety of conventional organic solvents.  The nucleating (or anti-nucleating) influence of assorted impurities is also a subject of interest.
Uric Acid is a known component of human kidney stones and gouty deposits.  Fundamental AFM studies provide insight into how solution parameters (e.g. pH, supersaturation, impurities) affect crystal growth kinetics and/or mechanisms.  Complementary experiments using microspectrometry are used to elucidate recognition events between the crystal surface and designer impurities. 
2.  Crystal Growth With 2D- and 3D- Templates
Crystal Growth in Gels has been used for over a century as a method for growing metals and inorganic crystals, but the details of nucleation and growth within these media are not well understood on the molecular-level.  Our fundamental studies seek to understand how intermolecular interactions between the gel and crystal can be exploited to access unusual crystal morphologies, affect chiral separations and/or template the growth of new polymorphic phases. 
Self Assembled Monolayers can be very effective templates for the growth of a variety of moleuclar crystals.  The rational design and testing of a series of SAMs with controlled functionality and lattice spacing, provides a means to construct a combinatorial library of 2D templates for molecular crystal growth studies. 
In the NewsCrystal Clear Persuasion
The Department of Chemistry's Jennifer Swift is launching a war on crystals that cause gallstones or kidney stones, hoping to slow down their growth and understand what makes them tick. June 1, 2005
Chemistry Professor Honored with Achievement Award
Professor Jennifer Swift has received the 2005 Margaret C. Etter Early Career Award. The annual award recognizes scientists who have made outstanding achievements and shown great potential at early stages of their careers. January 12, 2005
Georgetown Recognizes Outstanding Faculty
Georgetown University awarded professors Norman J. Finkel, Nicoletta Pireddu and Jennifer Swift the College Dean Awards for Excellence in Teaching at the 2005-2006 College Faculty Convocation on November 14, 2005. 
Recent PublicationsRupa Hiremath, Joseph A. Basile, Stephen W. Varney, and Jennifer A. Swift, “Controlling Polymorphism of Molecular Crystals with Self-Assembled Monolayer Templates,” J. Am. Chem. Soc., 127, 18321-18327 (2005).
Richard S. Abendan and Jennifer A. Swift, “ Dissolution on Cholesterol Monohydrate Single Crystal Surfaces Monitored by In Situ Atomic Force Microscopy ,” Crystal Growth & Design, 5(6), 2146-2153 (2005).
Ryan E. Sours, Amanuel Z. Zellelow and Jennifer A. Swift, “An in situ Atomic Force Microscopy Study of Uric Acid Crystal Growth,” J. Phys. Chem B, 109, 9989-9995 (2005).
Rupa Hiremath, Stephen W. Varney and Jennifer A. Swift, “Oriented Crystal Growth of 4-Iodo-4’-Nitrobiphenyl on Polar Self-Assembled Monolayer Templates: a Case for “Chemical Epitaxy”,” Chem. Mater., 16, 24, 4948- 4954 (2004).
M. Crina Frincu, Sean D. Fleming, Andrew L. Rohl and Jennifer A. Swift, “The Epitaxial Growth of Cholesterol Crystals from Model Bile Solutions on Calcite Substrates,” J. Am. Chem. Soc., 126, 25, 7915 – 7924 (2004).
   page last updated: April 19, 2006
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