F1000 Biology Reports

The F1000 Biology Reports (ISSN 1757-594X) journal publishes short commentaries by the world's top scientists in which the hottest biology papers/clusters of papers identified by Faculty of 1000 are put into a broader context.

Latest Articles

• Cell Biology

  Role of caspases and non-caspase proteases in cell death

  Jisen Huai, Lars Jöckel, Karen Schrader and Christoph Borner

  F1000 Biology Reports 2010, 2:48 (23 June 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Transport vesicle uncoating: it's later than you think

  Meg Trahey and Jesse C Hay

  F1000 Biology Reports 2010, 2:47 (23 June 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience

  De novo prions

  Federico Benetti, Michael D Geschwind and Giuseppe Legname

  F1000 Biology Reports 2010, 2:46 (23 June 2010)

  [Abstract] [Full text] [PDF]

• Microbiology/Cell Biology

  Autophagy of intracellular microbes and mitochondria: two sides of the same coin?

  Vojo Deretic

  F1000 Biology Reports 2010, 2:45 (23 June 2010)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics

  Retrotransposons and germ cells: reproduction, death, and diversity

  Stefanie Seisenberger, Christian Popp and Wolf Reik

  F1000 Biology Reports 2010, 2:44 (16 June 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience

  An uncorrelated state for the cortex?

  David P A Schulz and Matteo Carandini

  F1000 Biology Reports 2010, 2:43 (16 June 2010)

  [Abstract] [Full text] [PDF]

• Microbiology/Immunology

  Do apicomplexan parasites hijack the host cell microRNA pathway for their intracellular development?

  Mohamed-Ali Hakimi and Robert Ménard

  F1000 Biology Reports 2010, 2:42 (16 June 2010)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Neuroscience

  Advances in the genetics of primary torsion dystonia

  Enza Maria Valente and Alberto Albanese

  F1000 Biology Reports 2010, 2:41 (16 June 2010)

  [Abstract] [Full text] [PDF]

• Immunology

  The role of IL-23 in the immunopathogenesis of psoriasis

  Paola Di Meglio and Frank O Nestle

  F1000 Biology Reports 2010, 2:40 (24 May 2010)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Structure of spliceosomal ribonucleoproteins

  Daniel Aaron Pomeranz Krummel, Kiyoshi Nagai and Chris Oubridge

  F1000 Biology Reports 2010, 2:39 (24 May 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience/Cell Biology

  Destroy to create: E3 ubiquitin ligases in neurogenesis

  Judith Stegmüller and Azad Bonni

  F1000 Biology Reports 2010, 2:38 (24 May 2010)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Cell Biology

  PRDM9 sticks its zinc fingers into recombination hotspots and between species

  Ionel Sandovici and Carmen Sapienza

  F1000 Biology Reports 2010, 2:37 (24 May 2010)

  [Abstract] [Full text] [PDF]

• Microbiology/Immunology

  Bacterial surface proteins and vaccines

  Guido Grandi

  F1000 Biology Reports 2010, 2:36 (11 May 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology/Structural Biology

  Membrane deformation and separation

  Rainer Beck, Britta Bruegger and Felix T Wieland

  F1000 Biology Reports 2010, 2:35 (11 May 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Seeing with the mind's eye: top-down, bottom-up, and conscious awareness

  Alumit Ishai

  F1000 Biology Reports 2010, 2:34 (11 May 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology

  A virtual cycle: theory and experiment converge on the exit from mitosis

  Karl A Merrick and Robert P Fisher

  F1000 Biology Reports 2010, 2:33 (11 May 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Recent advances in understanding Golgi biogenesis

  Suzanne R Pfeffer

  F1000 Biology Reports 2010, 2:32 (27 April 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology/Structural Biology/Chemical Biology

  Understanding lipid rafts and other related membrane domains

  Aaron K Neumann, Michelle S Itano and Ken Jacobson

  F1000 Biology Reports 2010, 2:31 (27 April 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology/Developmental Biology

  Doing cell biology in embryos: regulated membrane traffic and its implications for cadherin biology

  Aparna Ratheesh and Alpha S Yap

  F1000 Biology Reports 2010, 2:30 (27 April 2010)

  [Abstract] [Full text] [PDF]

• Microbiology/Immunology

  Why is Pseudomonas aeruginosa a pathogen?

  Joanna B Goldberg

  F1000 Biology Reports 2010, 2:29 (27 April 2010)

  [Abstract] [Full text] [PDF]

• Chemical Biology/Cell Biology

  LOV conquers (sm)All GTPases

  Rachelle Kosoff and Jonathan Chernoff

  F1000 Biology Reports 2010, 2:28 (12 April 2010)

  [Abstract] [Full text] [PDF]

• Immunology/Microbiology

  Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses

  Andrew S Neish and Timothy L Denning

  F1000 Biology Reports 2010, 2:27 (12 April 2010)

  [Abstract] [Full text] [PDF]

• Microbiology/Pharmacology & Drug Discovery

  The garden of antimicrobial delights

  Julian Davies

  F1000 Biology Reports 2010, 2:26 (12 April 2010)

  [Abstract] [Full text] [PDF]

• Plant Biology

  Plant asymmetric cell division regulators: pinch-hitting for PARs?

  Carrie A Metzinger and Dominique C Bergmann

  F1000 Biology Reports 2010, 2:25 (12 April 2010)

  [Abstract] [Full text] [PDF]

• Microbiology

  Recent insights into fatty acid acquisition and metabolism in malarial parasites

  Bamini Jayabalasingham, Robert Menard and David A Fidock

  F1000 Biology Reports 2010, 2:24 (25 March 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology/Immunology

  Epigenetic regulation of antigen receptor gene rearrangement

  Salvatore Spicuglia, Joaquin Zacarias-Cabeza, Aleksandra Pekowska and Pierre Ferrier

  F1000 Biology Reports 2010, 2:23 (25 March 2010)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Physiology

  Genetics of pulmonary arterial hypertension: do the molecular findings have translational value?

  Nicholas W Morrell

  F1000 Biology Reports 2010, 2:22 (25 March 2010)

  [Abstract] [Full text] [PDF]

• Immunology/Neuroscience

  An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome

  Kazim A Sheikh and Gang Zhang

  F1000 Biology Reports 2010, 2:21 (25 March 2010)

  [Abstract] [Full text] [PDF]

• Structural Biology/Cell Biology

  Recent advances in polyubiquitin chain recognition

  Hao Wu, Yu-Chih Lo and Su-Chang Lin

  F1000 Biology Reports 2010, 2:20 (15 March 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Control of Schwann cell myelination

  Kristján R Jessen and Rhona Mirsky

  F1000 Biology Reports 2010, 2:19 (15 March 2010)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Cell Biology

  Mapping chromatin conformation

  Peter J Shaw

  F1000 Biology Reports 2010, 2:18 (15 March 2010)

  [Abstract] [Full text] [PDF]

• Developmental Biology

  Recent advances in pancreas development: from embryonic pathways to programming renewable sources of beta cells

  Victoria E Prince and Mary D Kinkel

  F1000 Biology Reports 2010, 2:17 (15 March 2010)

  [Abstract] [Full text] [PDF]

• Physiology

  The pathophysiology of diastolic heart failure

  Thanh Trung Phan and Michael Frenneaux

  F1000 Biology Reports 2010, 2:16 (24 February 2010)

  [Abstract] [Full text] [PDF]

• Plant Biology

  Abscisic acid (ABA) receptors: light at the end of the tunnel

  Jorge Muschietti and Sheila McCormick

  F1000 Biology Reports 2010, 2:15 (24 February 2010)

  [Abstract] [Full text] [PDF]

• Immunology

  Regulation of the IgE response

  Daniel H Conrad, David R Gibb and Jamie Sturgill

  F1000 Biology Reports 2010, 2:14 (24 February 2010)

  [Abstract] [Full text] [PDF]

• Physiology/Neuroscience

  Stress and eating behaviour

  Achim Peters and Dirk Langemann

  F1000 Biology Reports 2010, 2:13 (24 February 2010)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery

  TRPV4 as a target for bladder overactivity

  Patrizia Angelico and Rodolfo Testa

  F1000 Biology Reports 2010, 2:12 (11 February 2010)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Neuroscience

  Distinct disorders affecting the brain share common genetic origins

  R Frank Kooy

  F1000 Biology Reports 2010, 2:11 (11 February 2010)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery/Cell Biology

  PARP inhibitors in BRCA1/BRCA2 germline mutation carriers with ovarian and breast cancer

  Christina M Annunziata and Susan E Bates

  F1000 Biology Reports 2010, 2:10 (11 February 2010)

  [Abstract] [Full text] [PDF]

• Plant Biology

  Recent advances in regulation of flowering

  Julin N Maloof

  F1000 Biology Reports 2010, 2:9 (11 February 2010)

  [Abstract] [Full text] [PDF]

• Structural Biology

  RNA pseudoknots: folding and finding

  Biao Liu, David H Mathews and Douglas H Turner

  F1000 Biology Reports 2010, 2:8 (27 January 2010)

  [Abstract] [Full text] [PDF]

• Plant Biology

  Recent advances in plant metabolomics and greener pastures

  Lloyd W Sumner

  F1000 Biology Reports 2010, 2:7 (27 January 2010)

  [Abstract] [Full text] [PDF]

• Developmental Biology/Neuroscience

  Mechanisms of growth cone repulsion

  Catherine E Krull and Judith S Eisen

  F1000 Biology Reports 2010, 2:6 (27 January 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Neuronal calcium sensor proteins: emerging roles in membrane traffic and synaptic plasticity

  Robert D Burgoyne and Lee P Haynes

  F1000 Biology Reports 2010, 2:5 (27 January 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Dysfunction of the Ca_V2.1 calcium channel in cerebellar ataxias

  Sanjeev Rajakulendran, Stephanie Schorge, Dimitri M Kullmann and Michael G Hanna

  F1000 Biology Reports 2010, 2:4 (18 January 2010)

  [Abstract] [Full text] [PDF]

• Immunology

  Ocular immune privilege

  Ru Zhou and Rachel R Caspi

  F1000 Biology Reports 2010, 2:3 (18 January 2010)

  [Abstract] [Full text] [PDF]

• Neuroscience/Physiology

  Multiple functions of dopamine neurons

  Wolfram Schultz

  F1000 Biology Reports 2010, 2:2 (18 January 2010)

  [Abstract] [Full text] [PDF]

• Ecology

  Eco-evolutionary dynamics: intertwining ecological and evolutionary processes in contemporary time

  Eric P Palkovacs and Andrew P Hendry

  F1000 Biology Reports 2010, 2:1 (18 January 2010)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4

  Cheng-Ming Chiang

  F1000 Biology Reports 2009, 1:98 (15 December 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  Natural killer T cell recognition of lipid antigens

  Luc Teyton

  F1000 Biology Reports 2009, 1:97 (15 December 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Putative functions of caspase-2

  Loretta Dorstyn and Sharad Kumar

  F1000 Biology Reports 2009, 1:96 (15 December 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Microbiology

  CRISPR-Cas: an adaptive immunity system in prokaryotes

  Eugene V Koonin and Kira S Makarova

  F1000 Biology Reports 2009, 1:95 (9 December 2009)

  [Abstract] [Full text] [PDF]

• Ecology

  Current themes and recent advances in modelling species occurrences

  Graeme S Cumming

  F1000 Biology Reports 2009, 1:94 (9 December 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology/Plant Biology

  Aberrant mRNA transcripts and nonsense-mediated decay

  Laura Trinkle-Mulcahy

  F1000 Biology Reports 2009, 1:93 (9 December 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Cell Biology/Developmental Biology

  Insulators: linking genome architecture to gene regulation

  Robert AH White

  F1000 Biology Reports 2009, 1:92 (9 December 2009)

  [Abstract] [Full text] [PDF]

• Chemical Biology/Genomics & Genetics/Structural Biology

  Prediction of function in protein superfamilies

  Shelley D Copley

  F1000 Biology Reports 2009, 1:91 (9 December 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Telomeric RNAs as a novel player in telomeric integrity

  Olaf Isken and Lynne E Maquat

  F1000 Biology Reports 2009, 1:90 (26 November 2009)

  [Abstract] [Full text] [PDF]

• Immunology/Microbiology

  HIV vaccination: turning the spotlight on effector memory T cells as mucosal gatekeepers

  Hilde Cheroutre

  F1000 Biology Reports 2009, 1:89 (26 November 2009)

  [Abstract] [Full text] [PDF]

• Chemical Biology/Structural Biology

  Unnatural amino acids: better than the real things?

  Ellen C Minnihan, Kenichi Yokoyama and JoAnne Stubbe

  F1000 Biology Reports 2009, 1:88 (26 November 2009)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery/Structural Biology

  Biased agonism

  Terry Kenakin

  F1000 Biology Reports 2009, 1:87 (26 November 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Cell Biology

  A direct measurement of crossing over in human prophase oocytes

  R Scott Hawley

  F1000 Biology Reports 2009, 1:86 (16 November 2009)

  [Abstract] [Full text] [PDF]

• Physiology/Neuroscience

  The evolving story of orexin biology: the hits keep coming

  Willis K Samson

  F1000 Biology Reports 2009, 1:85 (16 November 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology/Developmental Biology

  Induced pluripotent stem (iPS) cells: an up-to-the-minute review

  Frank Lau, Tim Ahfeldt, Kenji Osafune, Hidenori Akustsu and Chad A Cowan

  F1000 Biology Reports 2009, 1:84 (16 November 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  An old dog learns new tricks: novel functions of the exocyst complex in polarized epithelia in animals

  Richard S Kang and Heike Fölsch

  F1000 Biology Reports 2009, 1:83 (16 November 2009)

  [Abstract] [Full text] [PDF]

• Ecology

  Evaluation of global change impacts on diffuse pollution

  Gilles Pinay and David M Hannah

  F1000 Biology Reports 2009, 1:82 (29 October 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Transcranial magnetic stimulation studies of visuospatial attentional control

  Sara M Szczepanski and Sabine Kastner

  F1000 Biology Reports 2009, 1:81 (29 October 2009)

  [Abstract] [Full text] [PDF]

• Immunology/Microbiology

  Genetic reprogramming of host cells by bacterial pathogens

  Guy Tran Van Nhieu and Laurence Arbibe

  F1000 Biology Reports 2009, 1:80 (29 October 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology/Pharmacology & Drug Discovery

  Inhibitor of Apoptosis (IAP) proteins as drug targets for the treatment of cancer

  David L Vaux

  F1000 Biology Reports 2009, 1:79 (29 October 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Music drives brain plasticity

  Lutz Jäncke

  F1000 Biology Reports 2009, 1:78 (14 October 2009)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery/Structural Biology

  Bitopic ligands: all-in-one orthosteric and allosteric

  Maud Kamal and Ralf Jockers

  F1000 Biology Reports 2009, 1:77 (14 October 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology/Genomics & Genetics

  When transcription meets recombination: a lesson from the human RECQ protein complexes

  Yilun Liu and Joan W Conaway

  F1000 Biology Reports 2009, 1:76 (14 October 2009)

  [Abstract] [Full text] [PDF]

• Physiology

  'Functional' body composition: differentiating between benign and non-benign obesity

  Manfred J Müller, Anja Bosy-Westphal, Martin Heller

  F1000 Biology Reports 2009, 1:75 (14 October 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience

  The posterior parietal cortex and non-spatial cognition

  Yumiko Yamazaki, Teruo Hashimoto and Atsushi Iriki

  F1000 Biology Reports 2009, 1:74 (28 September 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Pharmacology & Drug Discovery

  Customized care 2020: how medical sequencing and network biology will enable personalized medicine

  Mark S Boguski, Ramy Arnaout and Colin Hill

  F1000 Biology Reports 2009, 1:73 (28 September 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology/Structural Biology

  Conformational changes in receptor tyrosine kinase signaling: an ErbB garden of delights

  Kermit L Carraway and Goldi A Kozloski

  F1000 Biology Reports 2009, 1:72 (28 September 2009)

  [Abstract] [Full text] [PDF]

• Microbiology

  HIV-1 host interactions: integration of large-scale datasets

  Amalio Telenti

  F1000 Biology Reports 2009, 1:71 (28 September 2009)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery/Immunology

  Targeting cytokines in inflammatory diseases: focus on interleukin-1-mediated autoinflammation

  George D Kalliolias and Lionel B Ivashkiv

  F1000 Biology Reports 2009, 1:70 (14 September 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Diversity of protein structures and difficulties in fold recognition: the curious case of protein G

  Jeremy Horst and Ram Samudrala

  F1000 Biology Reports 2009, 1:69 (14 September 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  The roles, mechanisms, and controversies of autophagy in mammalian biology

  Russell G Jones

  F1000 Biology Reports 2009, 1:68 (14 September 2009)

  [Abstract] [Full text] [PDF]

• Immunology/Cell Biology

  Integrin-independent movement of immune cells

  Sophie E Pinner and Erik Sahai

  F1000 Biology Reports 2009, 1:67 (14 September 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Setting the absolute threshold of vision

  Alapakkam P Sampath and Gordon L Fain

  F1000 Biology Reports 2009, 1:66 (26 August 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers

  Anna K Townley and David J Stephens

  F1000 Biology Reports 2009, 1:65 (26 August 2009)

  [Abstract] [Full text] [PDF]

• Microbiology

  Do apicomplexan parasite-encoded proteins act as both ligands and receptors during host cell invasion?

  Paul R Gilson and Brendan S Crabb

  F1000 Biology Reports 2009, 1:64 (26 August 2009)

  [Abstract] [Full text] [PDF]

• Physiology

  Depression and metabolism: linking changes in leptin and ghrelin to mood

  Michael Lutter and Joel Elmquist

  F1000 Biology Reports 2009, 1:63 (26 August 2009)

  [Abstract] [Full text] [PDF]

• Microbiology

  Cryptococcus gattii outbreak expands into the Northwestern United States with fatal consequences

  Edmond J Byrnes III and Joseph Heitman

  F1000 Biology Reports 2009, 1:62 (17 August 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience/Immunology

  Autoimmune channelopathies: new antibody-mediated disorders of the central nervous system

  Angela Vincent

  F1000 Biology Reports 2009, 1:61 (17 August 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  Thymic egress: S1P of 1000

  Marcus A Zachariah and Jason G Cyster

  F1000 Biology Reports 2009, 1:60 (17 August 2009)

  [Abstract] [Full text] [PDF]

• Developmental Biology/Cell Biology

  Intracellular trafficking and signaling in development

  Daniel B Constam

  F1000 Biology Reports 2009, 1:59 (17 August 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology/Neuroscience

  Cell biology of mechanotransduction in inner-ear hair cells

  David P Corey

  F1000 Biology Reports 2009, 1:58 (27 July 2009)

  [Abstract] [Full text] [PDF]

• Plant Biology

  The dark side of clock-controlled flowering

  Vicente Rubio and Xing Wang Deng

  F1000 Biology Reports 2009, 1:57 (27 July 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience/Developmental Biology

  Development of object recognition in humans

  Mayu Nishimura, Suzy Scherf and Marlene Behrmann

  F1000 Biology Reports 2009, 1:56 (27 July 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  Two mechanisms that account for major histocompatibility complex restriction of T cells

  David M Kranz

  F1000 Biology Reports 2009, 1:55 (27 July 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience

  A current view of Alzheimer's disease

  Basavaraj V Hooli and Rudolph E Tanzi

  F1000 Biology Reports 2009, 1:54 (08 July 2009)

  [Abstract] [Full text] [PDF]

• Chemical Biology/Pharmacology & Drug Discovery

  Using the ribosome to synthesize peptidomimetics

  Roger M Freidinger

  F1000 Biology Reports 2009, 1:53 (08 July 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Microtubule motors: moving forward on many fronts

  Viki Allan

  F1000 Biology Reports 2009, 1:52 (08 July 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Molecular dynamics-based approaches for enhanced sampling of long-time, large-scale conformational changes in biomolecules

  Tamar Schlick

  F1000 Biology Reports 2009, 1:51 (08 July 2009)

  [Abstract] [Full text] [PDF]

• Microbiology/Immunology

  Lessons from the failure of the adenovector HIV vaccine

  Marie-Eve Blais and Sarah Rowland-Jones

  F1000 Biology Reports 2009, 1:50 (29 June 2009)

  [Abstract] [Full text] [PDF]

• Developmental Biology

  Clearance of germ granules in the soma

  Asako Sugimoto

  F1000 Biology Reports 2009, 1:49 (29 June 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Monte Carlo, harmonic approximation, and coarse-graining approaches for enhanced sampling of biomolecular structure

  Tamar Schlick

  F1000 Biology Reports 2009, 1:48 (29 June 2009)

  [Abstract] [Full text] [PDF]

• Plant Biology

  The role of malate in plant homeostasis

  Iris Finkemeier and Lee J Sweetlove

  F1000 Biology Reports 2009, 1:47 (29 June 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience/Physiology

  Purinergic cotransmission

  Geoffrey Burnstock

  F1000 Biology Reports 2009, 1:46 (09 June 2009)

  [Abstract] [Full text] [PDF]

• Plant Biology

  Shaping the meristem by mechanical forces

  Patrick Laufs, Alexis Peaucelle and Herman Höfte

  F1000 Biology Reports 2009, 1:45 (09 June 2009)

  [Abstract] [Full text] [PDF]

• Ecology

  Extinction risks from climate change: macroecological and historical insights

  Roland Jansson

  F1000 Biology Reports 2009, 1:44 (09 June 2009)

  [Abstract] [Full text] [PDF]

• Ecology

  Evolutionary impacts of fishing: overfishing's 'Darwinian debt'

  John M Pandolfi

  F1000 Biology Reports 2009, 1:43 (09 June 2009)

  [Abstract] [Full text] [PDF]

• Immunology/Physiology

  Role of neuropeptides, hormones, and growth factors in regulating thymopoiesis in middle to old age

  Kalpesh Patel and Dennis D Taub

  F1000 Biology Reports 2009, 1:42 (28 May 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Osmolyte solutions and protein folding

  Char Y Hu, B Montgomery Pettitt and Joerg Roesgen

  F1000 Biology Reports 2009, 1:41 (28 May 2009)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery

  New antibiotics for antibiotic-resistant bacteria

  William Stubbings and Harald Labischinski

  F1000 Biology Reports 2009, 1:40 (28 May 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  B cell-targeted therapies in autoimmunity: rationale and progress

  Paolo Fiorina and Mohamed H Sayegh

  F1000 Biology Reports 2009, 1:39 (28 May 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Describing protein conformational ensembles: beyond static snapshots

  George N Phillips, Jr

  F1000 Biology Reports 2009, 1:38 (08 May 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology/Chemical Biology

  Detailed mechanism for transposition by TnpA transposase involves DNA -shape rather than direct protein-DNA recognition to generate an active nucleoprotein complex

  P Shing Ho

  F1000 Biology Reports 2009, 1:37 (08 May 2009)

  [Abstract] [Full text] [PDF]

• Ecology

  The consequences of human-driven ocean acidification for marine life

  Scott Doney

  F1000 Biology Reports 2009, 1:36 (08 May 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Pharmacology & Drug Discovery

  Emerging technologies for the genomic analysis of cancer

  John Nemunaitis and Neil N Senzer

  F1000 Biology Reports 2009, 1:35 (08 May 2009)

  [Abstract] [Full text] [PDF]

• Microbiology

  Electron transport chains of lactic acid bacteria - walking on crutches is part of their lifestyle

  Rob Brooijmans, Willem M de Vos, and Jeroen Hugenholtz

  F1000 Biology Reports 2009, 1:34 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Cell Biology

  Ubiquitous antisense transcription in eukaryotes: novel regulatory mechanism or byproduct of opportunistic RNA polymerase?

  Justin H Layer and P Anthony Weil

  F1000 Biology Reports 2009, 1:33 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics

  Applications of high-throughput sequencing to chromatin structure and function in mammals

  Ian Dunham

  F1000 Biology Reports 2009, 1:32 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Plant Biology

  Long-distance transport of macromolecules through the phloem

  Julia Kehr

  F1000 Biology Reports 2009, 1:31 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Microbiology/Immunology

  The role of microbial polysaccharides in host-pathogen interaction

  David Corbett and Ian S. Roberts

  F1000 Biology Reports 2009, 1:30 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology/Chemical Biology

  Single-molecule dynamics of nuclear mRNA

  Yaron Shav-Tal and Yosef Gruenbaum

  F1000 Biology Reports 2009, 1:29 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  A novel mucosal RORµt+NKp46+ cell subset is a source of interleukin-22

  Elena Tomasello, Ana Reynders and Eric Vivier

  F1000 Biology Reports 2009, 1:28 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience/Developmental Biology

  The growth cone: an integrator of unique cues into refined axon guidance

  Sophie Chauvet and Geneviève Rougon

  F1000 Biology Reports 2009, 1:27 (29 April 2009)

  [Abstract] [Full text] [PDF]

• Ecology

  Toward understanding the effect of top predators on ecosystems

  Nicolas Lecomte, Dorothée Ehrich, Rolf A Ims and Nigel G Yoccoz

  F1000 Biology Reports 2009, 1:26 (24 March 2009)

  [Abstract] [Full text] [PDF]

• Genomics & Genetics/Microbiology

  Bioinformatic detection of horizontally transferred DNA in bacterial genomes

  Morgan GI Langille and Fiona SL Brinkman

  F1000 Biology Reports 2009, 1:25 (24 March 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Nuclear magnetic resonance captures the elusive

  Steven R Van Doren

  F1000 Biology Reports 2009, 1:24 (24 March 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience/Pharmacology & Drug Discovery

  The ABCB1 transporter gene and antidepressant response

  Eric J Peters, Victor Reus and Steven P Hamilton

  F1000 Biology Reports 2009, 1:23 (24 March 2009)

  [Abstract] [Full text] [PDF]

• Microbiology

  Latest advances in innate antiviral defence

  Aaron Irving and Bryan RG Williams

  F1000 Biology Reports 2009, 1:22 (17 March 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  'A mover and a shaker': 53BP1 allows DNA doublestrand breaks a chance to dance and unite

  Aaron A Goodarzi and Penny A Jeggo

  F1000 Biology Reports 2009, 1:21 (17 March 2009)

  [Abstract] [Full text] [PDF]

• Developmental Biology

  Breaking the A chain: regulating mRNAs in development through CCR4 deadenylase

  Jocelyn Moore and Paul Lasko

  F1000 Biology Reports 2009, 1:20 (17 March 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology/Chemical Biology

  All change: protein conformation and the ubiquitination reaction cascade

  Christiane Riedinger and Jane A Endicott

  F1000 Biology Reports 2009, 1:19 (17 March 2009)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery/Microbiology

  Malarial parasite pathogenesis and drug targets

  Paul D Roepe

  F1000 Biology Reports 2009, 1:18 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Mitochondria and apoptosis: a quick take on a long view

  Melissa J Parsons and Douglas R Green

  F1000 Biology Reports 2009, 1:17 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Ecology

  Climate change and biodiversity conservation: impacts, adaptation strategies and future research directions

  Shannon M Hagerman and Kai MA Chan

  F1000 Biology Reports 2009, 1:16 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  The inflammasome and alum-mediated adjuvanticity

  Suk-Jo Kang and Richard M Locksley

  F1000 Biology Reports 2009, 1:15 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Plant Biology

  Trace elements: too little or too much and how plants cope

  Joe Morrissey and Mary Lou Guerinot

  F1000 Biology Reports 2009, 1:14 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Regulatory roles of the cadherin superfamily

  Robert Harmon, Bhushan Desai and Kathleen Green

  F1000 Biology Reports 2009, 1:13 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Microbiology/Immunology

  Recent strategies to identify broadly neutralizing antibodies against influenza A virus

  Donna M Tscherne and Adolfo García-Sastre

  F1000 Biology Reports 2009, 1:12 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  G-protein-coupled receptor structure: what can we learn?

  Andrew B Tobin

  F1000 Biology Reports 2009, 1:11 (24 February 2009)

  [Abstract] [Full text] [PDF]

• Physiology

  Central control of feeding

  Kristin A Anderson and Anthony R Means

  F1000 Biology Reports 2009, 1:10 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Microbiology/Immunology

  Gut commensal flora: tolerance and homeostasis

  Maria Rescigno

  F1000 Biology Reports 2009, 1:9 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Pharmacology & Drug Discovery/Cell Biology

  Regulation of the mTOR signaling pathway: from laboratory bench to bedside and back again

  Robert T Abraham

  F1000 Biology Reports 2009, 1:8 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  Implications of the RecA structure

  Edward H Egelman

  F1000 Biology Reports 2009, 1:7 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Structural Biology

  The unforeseeable hammerhead ribozyme

  Christian Hammann and Eric Westhof

  F1000 Biology Reports 2009, 1:6 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  Duality in the Th17-Treg developmental decision

  Robin D Hatton and Casey T Weaver

  F1000 Biology Reports 2009, 1:5 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Cell Biology

  Roles of the small GTPases RhoA and Rac1 in cell behavior

  Carol Otey, Silvia Goicoechea and Rafael Garcia-Mata

  F1000 Biology Reports 2009, 1:4 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience

  Sources of the spatial code within the hippocampus

  Mark P Brandon and Michael E Hasselmo

  F1000 Biology Reports 2009, 1:3 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Immunology

  Alternative macrophage activation and the regulation of metabolism

  Paul Webb

  F1000 Biology Reports 2009, 1:2 (21 January 2009)

  [Abstract] [Full text] [PDF]

• Neuroscience/Developmental Biology

  Recent advances in neural development

  Clemens Kiecker and Andrew Lumsden

  F1000 Biology Reports 2009, 1:1 (21 January 2009)

  [Abstract] [Full text] [PDF]