Part 1: A baffling illness
Faced with a confounding illness, doctors consider an extraordinary step sequencing 4-year-old Nicholas Volker's DNA.
Part 2: Sifting through the DNA haystack
Driven by the urgency of Nicholas' condition, researchers seek clues in his DNA and find more than they expected.
Part 3: Gene insights lead to a risky treatment
Armed with an answer that brings its own questions, Nicholas' doctors and parents weigh a risky treatment.
Read Genetics in Medicine's published study and commentary on Nicholas Volker's whole exome sequencing.
The 2011 Pullizer Prize for explanatory reporting was awarded to Mark Johnson, Kathleen Gallagher, Gary Porter, Lou Saldivar and Alison Sherwood for their "lucid examination of an epic effort to use genetic technology to save a 4-year-old boy imperiled by a mysterious disease, told with words, graphics, videos and other images."
Nicholas Volker is a little boy with a rare, devastating disease. In a desperate bid to save his life, Wisconsin doctors must decide: Is it time to push medicine's frontier?
Since leaving Children's Hospital of Wisconsin in October after an epic medical journey that spanned hundreds of days, Nic Volker, now 6, has been making steady progress. (1)
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