Jeremy is in Manchester tonight with all the action and analysis from the third day of the Conservative Party conference. There has been a bit of a catflap over human rights, is it the Tories' claws four moment? (Sorry....)

We'll have the annual conference season interview with the Mayor of London (you can re-watch the interviews from 2009, and 2010 here).

This year Jeremy asks Boris if he'd consider standing for Parliament while serving as Mayor, and is offered a hand from Boris should he ever decide to give up his day job presenting Newsnight and run for leader of the Conservative party.

And Jeremy will be joined by an audience of 70 Conservative women to discuss the reasons for the government's worsening polling with woman, and to work out what more the Conservatives could do to appeal to women.

Tonight's programme will come from the Tory party conference in Manchester, where Jeremy Paxman will be joined by an audience of conference attendees.

Jeremy will be speaking to MPs Philip Hammond, David Davis and Don Foster. Also we'll be getting the journalist's view of the conference from Fraser Nelson and Kevin Maguire.

The main topic for discussion will be the economy and Chancellor George Osborne's big speech today and David Grossman will be giving his analysis of what the chancellor said.

Plus Iain Watson will be looking at the European economic crisis amid the news that Greece is likely to miss targets to cut its budget deficit.

And as the government announces that it is going to invest £50m to commercialise graphene - a carbon allotrope invented at Manchester University - we ask what is it and why is it important?

UPDATE AT 1807 - Here's what is happening on tonight's programme:

In our final edition of the week, Andrew Verity will be asking what if anything is wrong with the predatory capitalism that Ed Miliband called for a clampdown on at the Labour Party's conference earlier this week.

Tim Whewell will have more on the news that US-born suspected al-Qaeda leader Anwar al-Awlaki, whose death was said to have been personally ordered by US President Barack Obama, has been killed in Yemen.

And as Amanda Knox and Raffaele Sollecito's appeal against their convictions for the 2007 murder of Perugia student Meredith Kercher draws to a close we ask what the obsession with Knox is and has it got anything to do with Berlusconi's Italy.

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ENTRY FROM 1137:

In our final edition of the week, Andrew Verity will be asking what's wrong with the predatory capitalism that Ed Miliband called for a clampdown on at the Labour Party's conference earlier this week.

US-born suspected al-Qaeda leader Anwar al-Awlaki, whose death was said to have been personally ordered by President Obama, has been killed in Yemen, reports say - we'll have more on that.

And the BBC's technology correspondent Rory Cellan-Jones has a piece about how US patent laws are threatening web development and innovation.

More details later.