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    Results: 1 to 20 of 97

    1.

    Antiproliferative and Antiplasmodial Dimeric Phloroglucinols from Mallotus oppositifolius from the Madagascar Dry Forest (1).

    Harinantenaina L, Bowman JD, Brodie PJ, Slebodnick C, Callmander MW, Rakotobe E, Randrianaivo R, Rasamison VE, Gorka A, Roepe PD, Cassera MB, Kingston DG.

    J Nat Prod. 2013 Mar 22;76(3):388-93. doi: 10.1021/np300750q. Epub 2013 Jan 3.

    PMID:
    23286240
    [PubMed - in process]
    2.

    Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth.

    Gorka AP, Alumasa JN, Sherlach KS, Jacobs LM, Nickley KB, Brower JP, de Dios AC, Roepe PD.

    Antimicrob Agents Chemother. 2013 Jan;57(1):356-64. doi: 10.1128/AAC.01709-12. Epub 2012 Oct 31.

    PMID:
    23114783
    [PubMed - in process]
    3.

    Relative to quinine and quinidine, their 9-epimers exhibit decreased cytostatic activity and altered heme binding but similar cytocidal activity versus Plasmodium falciparum.

    Gorka AP, Sherlach KS, de Dios AC, Roepe PD.

    Antimicrob Agents Chemother. 2013 Jan;57(1):365-74. doi: 10.1128/AAC.01234-12. Epub 2012 Oct 31.

    PMID:
    23114754
    [PubMed - in process]
    4.

    Autophagy in Apicomplexa: a life sustaining death mechanism?

    Sinai AP, Roepe PD.

    Trends Parasitol. 2012 Sep;28(9):358-64. doi: 10.1016/j.pt.2012.06.006. Epub 2012 Jul 18.

    PMID:
    22819059
    [PubMed - indexed for MEDLINE]
    5.

    Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum.

    Dinio T, Gorka AP, McGinniss A, Roepe PD, Morgan JB.

    Bioorg Med Chem. 2012 May 15;20(10):3292-7. doi: 10.1016/j.bmc.2012.03.042. Epub 2012 Mar 29.

    PMID:
    22512909
    [PubMed - indexed for MEDLINE]
    6.

    Autophagy is a cell death mechanism in Toxoplasma gondii.

    Ghosh D, Walton JL, Roepe PD, Sinai AP.

    Cell Microbiol. 2012 Apr;14(4):589-607. doi: 10.1111/j.1462-5822.2011.01745.x. Epub 2012 Feb 8.

    PMID:
    22212386
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Antiplasmodial and antiproliferative pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest.

    Pan E, Gorka AP, Alumasa JN, Slebodnick C, Harinantenaina L, Brodie PJ, Roepe PD, Randrianaivo R, Birkinshaw C, Kingston DG.

    J Nat Prod. 2011 Oct 28;74(10):2174-80. doi: 10.1021/np200499d. Epub 2011 Oct 13.

    PMID:
    21995542
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Quantification of perchloroethylene residues in dry-cleaned fabrics.

    Sherlach KS, Gorka AP, Dantzler A, Roepe PD.

    Environ Toxicol Chem. 2011 Nov;30(11):2481-7. doi: 10.1002/etc.665. Epub 2011 Sep 20.

    PMID:
    21898565
    [PubMed - indexed for MEDLINE]
    9.

    Analysis of chloroquine resistance transporter (CRT) isoforms and orthologues in S. cerevisiae yeast.

    Baro NK, Pooput C, Roepe PD.

    Biochemistry. 2011 Aug 9;50(31):6701-10. doi: 10.1021/bi200922g. Epub 2011 Jul 19.

    PMID:
    21744797
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Following the membrane potential by Nybo Kristie.

    Roepe P.

    Biotechniques. 2011 Mar;50(3):145. doi: 10.2144/000113622. No abstract available.

    PMID:
    21486232
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Plasmodium falciparum resistance to cytocidal versus cytostatic effects of chloroquine.

    Paguio MF, Bogle KL, Roepe PD.

    Mol Biochem Parasitol. 2011 Jul-Aug;178(1-2):1-6. doi: 10.1016/j.molbiopara.2011.03.003. Epub 2011 Apr 4.

    PMID:
    21470564
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    PfCRT-mediated drug transport in malarial parasites.

    Roepe PD.

    Biochemistry. 2011 Jan 18;50(2):163-71. Epub 2010 Dec 22. Review.

    PMID:
    21142008
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.

    Alumasa JN, Gorka AP, Casabianca LB, Comstock E, de Dios AC, Roepe PD.

    J Inorg Biochem. 2011 Mar;105(3):467-75. doi: 10.1016/j.jinorgbio.2010.08.011. Epub 2010 Sep 22.

    PMID:
    20864177
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross.

    Patel JJ, Thacker D, Tan JC, Pleeter P, Checkley L, Gonzales JM, Deng B, Roepe PD, Cooper RA, Ferdig MT.

    Mol Microbiol. 2010 Nov;78(3):770-87. doi: 10.1111/j.1365-2958.2010.07366.x. Epub 2010 Sep 29.

    PMID:
    20807203
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue.

    Pleeter P, Lekostaj JK, Roepe PD.

    Mol Biochem Parasitol. 2010 Oct;173(2):158-61. doi: 10.1016/j.molbiopara.2010.05.012. Epub 2010 Jun 1.

    PMID:
    20546803
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Reduced digestive vacuolar accumulation of chloroquine is not linked to resistance to chloroquine toxicity.

    Cabrera M, Paguio MF, Xie C, Roepe PD.

    Biochemistry. 2009 Dec 1;48(47):11152-4. doi: 10.1021/bi901765v.

    PMID:
    19883122
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Chloroquine transport in Plasmodium falciparum. 1. Influx and efflux kinetics for live trophozoite parasites using a novel fluorescent chloroquine probe.

    Cabrera M, Natarajan J, Paguio MF, Wolf C, Urbach JS, Roepe PD.

    Biochemistry. 2009 Oct 13;48(40):9471-81. doi: 10.1021/bi901034r.

    PMID:
    19728740
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Chloroquine transport in Plasmodium falciparum. 2. Analysis of PfCRT-mediated drug transport using proteoliposomes and a fluorescent chloroquine probe.

    Paguio MF, Cabrera M, Roepe PD.

    Biochemistry. 2009 Oct 13;48(40):9482-91. doi: 10.1021/bi901035j.

    PMID:
    19725576
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain.

    Iwaniuk DP, Whetmore ED, Rosa N, Ekoue-Kovi K, Alumasa J, de Dios AC, Roepe PD, Wolf C.

    Bioorg Med Chem. 2009 Sep 15;17(18):6560-6. doi: 10.1016/j.bmc.2009.08.003. Epub 2009 Aug 8.

    PMID:
    19703776
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    P. falciparum Na(+)/H(+) exchanger (PfNHE) function and quinine resistance (QNR) [Reply to: Spillman et al. "Acid extrusion from the intraerythrocytic malaria parasite is not via a Na(+)/H(+) exchanger" Mol. Biochem. Parasitol. 2008 162 (1) 96-99].

    Roepe PD, Ferdig MT.

    Mol Biochem Parasitol. 2009 Jul;166(1):1-2; author reply 3. doi: 10.1016/j.molbiopara.2009.01.008. Epub 2009 Apr 10. No abstract available.

    PMID:
    19428665
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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