DOI:​10.1006/GYNO.2000.6098
Corpus ID: 24235953
Management of recurrent juvenile granulosa cell tumor of the ovary.
J. L. Powell, G. P. Connor, G. Henderson
Published 2001
Medicine
Gynecologic oncology
BACKGROUND Juvenile granulosa cell tumors of the ovary are a rare form of neoplasm that makes up less than 5% of ovarian tumors in childhood and adolescence. About 90% are diagnosed in stage I with a… Expand
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37 Citations
Highly Influential Citations
1
Background Citations
9
Results Citations
1
Topics from this paper
Neoplasms
juvenile granulosa cell tumor
pediatric intracranial germ cell brain tumor
ovarian neoplasm
Carboplatin
Bleomycin
Paclitaxel
Etoposide
Granulosa cell tumor of the ovary
Recurrent disease
Cesarean section
Breech Presentation
Biomarkers, Tumor
Ovariectomy
Right Salpingo-Oophorectomy
Spleen Tissue
Tumor Debulking
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The case of a 4-year-old female presenting with symptoms of precocious puberty and diagnosed with juvenile GCT on the left ovary after surgical resection is reported, however, during follow-up 1 year after GCT resection, she presented with another multiloculated cystic mass in the right ovary and was diagnosed as SCA. Expand
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It seems that unilateral salpingo-oophorectomy followed by BEP chemotherapy is an appropriate treatment for unilateral Stage IC ovarian JGCT in women desiring to preserve ovarian function and childbearing capacity. Expand
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2004
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The results of the study showed that the mitotic index may be a valuable prognostic factor in patients with histologically proven granulosa cell tumor of the ovary, since residual tumor disease is associated with a poor prognosis. Expand
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A 10-year-old girl with stage IA JGCT, initially treated with resection only, presented with extensive unresectable multifocal pelvic recurrence and is in complete remission 69 months after her recurrence. Expand
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2003
TLDR
The pathology and treatment of women with granulosa cell tumours of the ovary is complex and such women should be managed in a multidisciplinary gynaecological oncology unit to guide therapy. Expand
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JGCT is a rare neoplasm with a wide morphologic spectrum and is easily confused with other tumors, and familiarity with the characteristics, rare atypical appearances, and immunohistochemical results may aid in obtaining a correct diagnosis. Expand
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152 Citations
Juvenile granulosa cell tumor of the ovary: A clinicopathological analysis of 125 cases
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Medicine
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TLDR
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: The clinical course and histologic features of 118 granulosa cell tumors and 82 theca cell tumors were reviewed. Although the 2 cell types are related, important differences exist in their… Expand
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TLDR
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N. Colombo, C. Sessa, F. Landoni, E. Sartori, S. Pecorelli, C. Mangioni
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TLDR
Six previously untreated women with recurrent and/or metastatic granulosa cell tumor of the ovary treated with cisplatin, vinblastine, and bleomycin in combination are alive and free of disease at a median follow-up time of 14 months from the start of treatment. Expand
125 Citations
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The results indicate that the combination of cisplatin, doxorubicin, and cyclophosphamide has modest activity in the treatment of metastatic ovarian stromal tumor.Expand
87 Citations
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G. Calaminus, R. Wessalowski, D. Harms, U. Göbel
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1997
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It is concluded that multidrug chemotherapy including cisplatin-based regimens may be useful to enhance treatment results of juvenile granulosa cell tumors, especially in advanced FIGO stages.
128 Citations
Late recurrence of juvenile granulosa cell tumor of the ovary.
Stephen D. Frausto, J. P. Geisler, M. Fletcher, A. Sood
Medicine
American journal of obstetrics and gynecology
2004
TLDR
The patient presented here was treated with a left oophorectomy after initial presentation, and remains disease free 19 months after this recurrence of JGCT in the left adnexa.
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