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Erythromycin

Known as: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione, Erythromycine, Erythromycin [Chemical/Ingredient] 
A broad-spectrum, macrolide antibiotic with antibacterial activity. Erythromycin diffuses through the bacterial cell membrane and reversibly binds to… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (24)

6,12-dideoxyerythromycin A6-O-methylerythromycin B8a-aza-8a-homoerythromycinA 63075
AstemizoleChlamydia InfectionsErythromycin / SulfisoxazoleErythromycin / Tretinoin

Broader (2)

Gastrointestinal AgentsMacrolide Antibiotics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Biogenic synthesis of silver nanoparticles and their synergistic effect with antibiotics: a study against gram-positive and gram-negative bacteria.
Highly Cited
2009
Highly Cited
2009
Characterization of a New Metallo-β-Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India
ABSTRACT A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a… 
Highly Cited
2009
Highly Cited
2009
Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment.
Highly Cited
2007
Highly Cited
2007
Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli.
Review
2000
Review
2000
Pathogenesis of group A streptococcal infections.
Group A streptococci are model extracellular gram-positive pathogens responsible for pharyngitis, impetigo, rheumatic fever, and… 
Highly Cited
1999
Highly Cited
1999
Occurrence of antibiotics in the aquatic environment.
Highly Cited
1997
Highly Cited
1997
The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. Finnish Study Group for Antimicrobial Resistance.
BACKGROUND In the early 1990s there was an increase in erythromycin resistance among group A streptococci in Finland. In response… 
Highly Cited
1996
Highly Cited
1996
Detection of erythromycin-resistant determinants by PCR
Erythromycin resistance determinants include Erm methylases, efflux pumps, and inactivating enzymes. To distinguish the different… 
Review
1995
Review
1995
Erythromycin resistance by ribosome modification
Erythromycin inhibits protein synthesis by its effect on ribosome function (14, 118, 119). The metabolic modifications that… 
Highly Cited
1990
Highly Cited
1990
An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea
ERYTHROMYCIN A, a clinically important polyketide antibiotic, is produced by the Gram-positive bacterium Saccharopolyspora… 
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