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Obesity

Known as: OBESE, Obesity NOS, adiposity 
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The… 
National Institutes of Health

Related topics

Related topics

49 relations
Appetite DepressantsAppetite DisordersAtkin syndromeBARDET-BIEDL SYNDROME 11

Narrower (5)

MOMES SyndromeMORM syndromeObesity, MorbidProopiomelanocortin Deficiency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Inflammatory links between obesity and metabolic disease.
The obesity epidemic has forced us to evaluate the role of inflammation in the health complications of obesity. This has led to a… 
Highly Cited
2006
Highly Cited
2006
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.
Review
2003
Review
2003
Fetal origins of obesity.
The worldwide epidemic of obesity continues unabated. Obesity is notoriously difficult to treat, and, thus, prevention is… 
Highly Cited
2002
Highly Cited
2002
Interleukin-6-deficient mice develop mature-onset obesity
The immune-modulating cytokine interleukin-6 (IL-6) is expressed both in adipose tissue and centrally in hypothalamic nuclei that… 
Highly Cited
2001
Highly Cited
2001
Ghrelin causes hyperphagia and obesity in rats.
Ghrelin, a circulating growth hormone-releasing peptide derived from the stomach, stimulates food intake. The lowest systemically… 
Highly Cited
2000
Highly Cited
2000
Lipotoxic heart disease in obese rats: implications for human obesity.
To determine the mechanism of the cardiac dilatation and reduced contractility of obese Zucker Diabetic Fatty rats, myocardial… 
Review
2000
Review
2000
Regulatory T cells
The phenomena of T cell–mediated suppression in immunologic tolerance have been controversial and remain an exciting area of… 
Highly Cited
1998
Highly Cited
1998
Aggresomes: A Cellular Response to Misfolded Proteins
Intracellular deposition of misfolded protein aggregates into ubiquitin-rich cytoplasmic inclusions is linked to the pathogenesis… 
Highly Cited
1996
Highly Cited
1996
IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance
Tumor necrosis factor-α (TNF-α) is an important mediator of insulin resistance in obesity and diabetes through its ability to… 
Highly Cited
1982
Highly Cited
1982
Relation of Body Fat Distribution to Metabolic Complications of Obesity
The importance of body fat distribution as a predictor of metabolic aberrations was evaluated in 9 nonobese and 25 obese… 
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