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Polycomb-Group Proteins

Known as: Polycomb-Group Protein, Polycomb Group Proteins, Polycomb Repressive Complex Proteins 
A family of proteins that play a role in CHROMATIN REMODELING. They are best known for silencing HOX GENES and the regulation of EPIGENETIC PROCESSES… 
National Institutes of Health

Related topics

Related topics

22 relations
BMI1 protein, humanChromatin Remodeling FactorDNA Topology RegulationEZH2 protein, human

Narrower (3)

Cbx8 protein, mousePolycomb Group (PcG) Multiprotein PRC1-Like Complexpho protein, Drosophila

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Transcriptional regulation by Polycomb group proteins
Polycomb group (PcG) proteins are epigenetic regulators of transcription that have key roles in stem-cell identity… 
Highly Cited
2008
Highly Cited
2008
Repression of E-cadherin by the polycomb group protein EZH2 in cancer
Enhancer of zeste homolog 2 (EZH2) is a critical component of the polycomb-repressive complex 2 (PRC2), which is involved in gene… 
Review
2007
Review
2007
Genome Regulation by Polycomb and Trithorax Proteins
Highly Cited
2007
Highly Cited
2007
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
Many genes associated with CpG islands undergo de novo methylation in cancer. Studies have suggested that the pattern of this… 
Highly Cited
2006
Highly Cited
2006
The Polycomb group protein EZH2 directly controls DNA methylation
The establishment and maintenance of epigenetic gene silencing is fundamental to cell determination and function. The essential… 
Highly Cited
2006
Highly Cited
2006
Genome-wide analysis of Polycomb targets in Drosophila melanogaster
Polycomb group (PcG) complexes are multiprotein assemblages that bind to chromatin and establish chromatin states leading to… 
Highly Cited
2004
Highly Cited
2004
Role of histone H2A ubiquitination in Polycomb silencing
Covalent modification of histones is important in regulating chromatin dynamics and transcription. One example of such… 
Review
2004
Review
2004
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins.
During the development of multicellular organisms, cells become different from one another by changing their genetic program in… 
Highly Cited
2004
Highly Cited
2004
Interaction of Polycomb-group proteins controlling flowering in Arabidopsis
In Arabidopsis, the EMBYRONIC FLOWER2 (EMF2), VERNALISATION2 (VRN2) and FERTILISATION INDEPENDENT ENDOSPERM2 (FIS2) genes encode… 
Highly Cited
1997
Highly Cited
1997
A Polycomb-group gene regulates homeotic gene expression in Arabidopsis
Cell fate is determined when the commitment of cells to a particular fate is autonomously maintained, irrespective of their… 
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