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Renal fibrosis

Known as: FIBROSIS KIDNEY, Kidney fibrosis, fibrosis kidneys 
Renal fibrosis is the consequence of an excessive accumulation of extracellular matrix that occurs in virtually every type of chronic kidney disease… 
National Institutes of Health

Related topics

Related topics

3 relations
Abnormal renal physiologyChronic tubulointerstitial nephritisarteriolonephrosclerosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
CD11c+ CD8+ T Cells Reduce Renal Fibrosis Following Ureteric Obstruction by Inducing Fibroblast Apoptosis
Tubulointerstitial fibrosis is a common consequence of various kidney diseases that lead to end-stage renal failure, and… 
Highly Cited
2011
Highly Cited
2011
TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29.
TGF-β/Smad3 signaling promotes fibrosis, but the development of therapeutic interventions involving this pathway will require the… 
Review
2010
Review
2010
Renal fibrosis: novel insights into mechanisms and therapeutic targets
Renal fibrosis is the common end point of virtually all progressive kidney diseases. Renal fibrosis should not be viewed as a… 
Highly Cited
2010
Highly Cited
2010
Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.
Smad2 and Smad3 interact and mediate TGF-beta signaling. Although Smad3 promotes fibrosis, the role of Smad2 in fibrogenesis is… 
Highly Cited
2009
Highly Cited
2009
Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice.
Diabetic nephropathy is the leading cause of chronic renal failure. Myofibroblasts play a major role in the synthesis and… 
Highly Cited
2009
Highly Cited
2009
Mesenchymal Stem Cells Attenuate Renal Fibrosis Through Immune Modulation and Remodeling Properties in a Rat Remnant Kidney Model
Mesenchymal stem cells (MSCs) have regenerative properties in acute kidney injury, but their role in chronic kidney diseases is… 
Review
2009
Review
2009
Renal tubulointerstitial fibrosis: common but never simple.
  • T. Hewitson
  • AJP - Renal Physiology
  • 2009
  • Corpus ID: 22135400
Regardless of etiology, all patients with chronic renal disease show a progressive decline in renal function with time. Fibrosis… 
Review
2004
Review
2004
The role of epithelial-to-mesenchymal transition in renal fibrosis
Epithelial-to-mesenchymal transition (EMT) involving injured epithelial cells plays an important role in the progression of… 
Review
2001
Review
2001
Angiotensin II and renal fibrosis.
Angiotensin (Ang) II, the main peptide of the renin angiotensin system (RAS), is a renal growth factor, inducing hyperplasia… 
Highly Cited
1998
Highly Cited
1998
Salt induces myocardial and renal fibrosis in normotensive and hypertensive rats.
BACKGROUND The detrimental effects of high dietary salt intake may not only involve effects on blood pressure and organ… 
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