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enfuvirtide

Known as: peptide T20, Envelope polyprotein GP160 precursor [Contains: Exterior membrane glycoprotein,GP120, Transmembrane glycoprotein,GP41], enfuvirtide [Chemical/Ingredient] 
A short polypeptide with activity against human immunodeficiency virus (HIV). Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 viral… 
National Institutes of Health

Related topics

Related topics

10 relations
Acquired Immunodeficiency SyndromeDrug AllergyEnfuvirtide:Susc:Pt:Isolate:OrdQn:GenotypingHIV Infections

Narrower (2)

DP 178Fuzeon

Broader (3)

HIV Envelope Protein gp41HIV Fusion InhibitorsPeptide Fragments

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Seeing Ourselves Through Technology: How We Use Selfies, Blogs and Wearable Devices to See and Shape Ourselves
Selfies, blogs and lifelogging devices help us understand ourselves, building on long histories of written, visual and… 
Highly Cited
2010
Highly Cited
2010
A Lectin Isolated from Bananas Is a Potent Inhibitor of HIV Replication*
BanLec is a jacalin-related lectin isolated from the fruit of bananas, Musa acuminata. This lectin binds to high mannose… 
Highly Cited
2005
Highly Cited
2005
Depletion of latent HIV-1 infection in vivo: a proof-of-concept study
Highly Cited
2005
Highly Cited
2005
Anti-Human Immunodeficiency Virus Type 1 (HIV-1) Antibodies 2F5 and 4E10 Require Surprisingly Few Crucial Residues in the Membrane-Proximal External Region of Glycoprotein gp41 To Neutralize HIV-1
ABSTRACT The conserved membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target… 
Highly Cited
2004
Highly Cited
2004
N-Substituted Pyrrole Derivatives as Novel Human Immunodeficiency Virus Type 1 Entry Inhibitors That Interfere with the gp41 Six-Helix Bundle Formation and Block Virus Fusion
ABSTRACT A recently approved peptidic human immunodeficiency virus type 1 (HIV-1) fusion inhibitor, T-20 (Fuzeon; Trimeris Inc… 
Review
2002
Review
2002
Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel.
OBJECTIVE New information warrants updated recommendations for the 4 central issues in antiretroviral therapy: when to start… 
Highly Cited
2001
Highly Cited
2001
New developments in anti-HIV chemotherapy
Highly Cited
1999
Highly Cited
1999
Inhibiting HIV-1 Entry Discovery of D-Peptide Inhibitors that Target the gp41 Coiled-Coil Pocket
Highly Cited
1998
Highly Cited
1998
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
T-20, a synthetic peptide corresponding to a region of the transmembrane subunit of the HIV-1 envelope protein, blocks cell… 
Highly Cited
1996
Highly Cited
1996
Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.
The synthetic peptides DP-107 and DP-178 (T-20), derived from separate domains within the human immunodeficiency virus type 1… 
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